BACKGROUND: Core Binding Factor or CBF is a transcription factor composed of two subunits. Runx1/AML-1 and CBF beta or CBFbeta. CBF was originally described as a regulator of hematopoiesis. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that CBF is involved in the control of skeletal muscle terminal differentiation. https://halohealthcarers.shop/product-category/cane-accessories/